Bad/Considerable Metabolizers, CYP2D6 The formation of your Energetic metabolite, M1, is mediated by CYP2D6, a polymorphic enzyme. Close to seven% in the populace has lessened activity of your CYP2D6 isoenzyme of cytochrome P450 metabolizing enzyme program. These people today are “bad metabolizers” of debrisoquine, dextromethorphan and tricyclic antidepressants, amid other https://nealed023fzs8.iyublog.com/profile