Poor/Comprehensive Metabolizers, CYP2D6 The development on the Energetic metabolite, M1, is mediated by CYP2D6, a polymorphic enzyme. Close to seven% in the populace has diminished action in the CYP2D6 isoenzyme of cytochrome P450 metabolizing enzyme procedure. These folks are “weak metabolizers” of debrisoquine, dextromethorphan and tricyclic antidepressants, among the other https://giordanot580bzx1.hyperionwiki.com/user