Pentobarbital will minimize the level or effect of artemether/lumefantrine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Coadministration with solid CYP3A4 inducers may end up in decreased serum concentrations and lack of antimalarial efficacy pentobarbital will lower the level or effect of diltiazem by impacting hepatic/intestinal enzyme https://zbigniewh261oyj7.blogoxo.com/profile