Pentobarbital will reduce the level or effect of midostaurin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Powerful CYP3A4 inducers may perhaps minimize midostaurin concentrations leading to diminished efficacy. Watch Carefully (one)pentobarbital will raise the degree or impact of clopidogrel by affecting hepatic/intestinal enzyme CYP3A4 metabo... https://annelik543wla0.wikiitemization.com/user